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Safety and efficacy of s-citalopram in patients with co-morbid major depression and diabetes mellitus

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In vitro/ex vivo studies conducted on endothelial cells showed that GLP-1RAs such as exenatide and liraglutide stimulate endothelial NO production and endothelial nitric oxide synthase (eNOS) activation, eliciting vasodilatation through activation of the GLP-1 receptor-dependent AMP-activated protein kinase (AMPK)/protein kinase B (Akt)/eNOS signaling pathway [48,49,50]

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All eight reported studies have demonstrated the noninferiority of GLP-1RAs compared to placebo regarding MACE

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Have direct mechanistic roles in acetaldehyde detoxification

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