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TABLE 4 Newcastle - Ottawa quality assessment scale for case-control studies
Lunov, O
A 1994 in vivo study by Natera, Jiang, and Ng extended the observation into a whole animal, reporting that chronic administration of synthetic hGH 177 to 191 to genetically obese (ob/ob) mice was associated with reduced cumulative body-weight gain and reduced adipose mass relative to controls [2]
The authors concluded that GHK acts by affecting TGF-1/Smad 2/3 and IGF-1 pathway
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