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"If you don't go to the gym and train while you're on these drugs, you just eat less shitty food and you take your already-low levels of muscle mass and dump them even further." "There's a situation people have described called 'Ozempic ass' and it's women who just diet their butts literally off totally flat." "It's a problem you've never seen exposed before because most of those people would have never dieted the weight off to begin with." Mr Curtis said, in his experience too, people with personal trainers are able to retain muscle while using semaglutide

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It helps modestly but isn't sufficient alone for most patients

GLP-1 and GLP-1(7-36) amide: influences on basal and stimulated insulin and glucagon secretion in the mouse