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While the R subunits are encoded by four separate genes (PRKAR1A and -B, PRKAR2A and -B), the catalytic subunits are primarily encoded by two major genes, PRKACA and PRKACB, which give rise to several tissue- and cell-specific splice variants, including immune cell-specific C2 (162, 163)
The study revealed striking sex-specific differences in how this oxidative damage manifests
As described above, folic acid plus pyridoxine treatment might effectively contribute to the reduction of the atherothrombotic risk (De Jong et al, 1999b
The Journal of Clinical Endocrinology & Metabolism
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