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Across randomized cardiovascular outcome trials and meta-analyses, SGLT2 inhibitors consistently reduce hospitalization for heart failure by approximately 3037% (hazard ratio [HR] 0.630.70), with benefits observed regardless of prior atherosclerotic cardiovascular disease status [6, 23]
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The commercial challenge then becomes how to maintain revenue when volume declines, he says
doi: 10.1210/jcem.74.4.1532179 36 WiersingaWM
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