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The mechanism underlying L-Carnitine's anti-obesity effects involves multiple pathways: facilitating long-chain fatty acid entry into mitochondria for oxidation, preventing accumulation of toxic lipid intermediates that impair insulin signaling, enhancing mitochondrial bioenergetics to support greater metabolic capacity, and modulating inflammatory pathways that contribute to metabolic dysfunction
Curcumin addresses microbial dysregulation through localized and systemic mechanisms
Jun 2006;29(6):831-40
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