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GHK-Cu , also referred to as Copper Tripeptide-1, is a naturally occurring complex of the tripeptide Glycyl-L-Histidyl-L-Lysine (GHK) bound to a copper(II) ion

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Among the different CEST MRI methods, glutamate CEST or GluCEST is sensitive to changes in levels of glutamate, the main excitatory neurotransmitter in the brain, which can be detected by targeting the amine proton at an offset frequency of 3 ppm (Cai et al., 2012)