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Unlike many therapeutic peptides that require cyclization or chemical modification to resist enzymatic breakdown, DSIP is a naturally occurring endogenous compound found in mammalian brain tissue, cerebrospinal fluid, blood plasma, and even peripheral organs
The primary mechanism of NO mediated wound healing is the formation of new blood vessels in a process called angiogenic repair
Intra-articular injection is not appropriate for all patients
Several peptides have evidence relevant to diabetic neuropathy
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