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If you're extremely constipated, it's best to talk with your doctor about using a laxative (such as an osmotic laxative or suppository) to remove the trapped stool
Heerspink HJL, Sattar N, Pavo I et al (2022) Effects of tirzepatide versus insulin glargine on kidney outcomes in type 2 diabetes in the SURPASS-4 trial: post-hoc analysis of an open-label, randomised, phase 3 trial
(PubMed) Kryscio RJ, Abner EL, Caban-Holt A, et al
Taking a Liposomal Vitamin C alongside your glutathione can create a more resilient antioxidant defense system
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