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The 1mg arm was a fixed low-dose cohort with no escalation

The most common B12/MIC side effect is pain, redness, or itching at the injection site

Conclusion Although changes in glutamate levels in schizophrenia have been linked to impaired glutamatergic neurotransmission and hypofunction of NMDA receptors, it is likely that glutamate alterations also result from metabolic impairments, particularly at mitochondrial level