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Modifier 59 applies to the second injection when multiple distinct injections are given

Medicare Part A and Part B may cover B12 shots if a doctor deems it medically necessary Medicare Part D is unlikely to cover B12 shots or oral supplements unless you can get it approved with a plan utilization management program B12 shots are used to treat a severe B12 deficiency that causes health issues such as fatigue and weakness, anemia, constipation, and more Does Medicare cover B12 shots

General Protocol Notes Specific dosing decisions should be made by the supervising physician, but several general principles guide this combination in clinical practice

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